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Details on Person p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
| Class:Id | LiteratureReference:9759063 |
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| _displayName | p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription |
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| _timestamp | 2021-11-29 20:38:17 |
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| author | [Person:5228790] Jain, Ashish
[Person:9664859] Lamark, Trond
[Person:9759065] Sjøttem, Eva
[Person:9759066] Larsen, Kenneth Bowitz
[Person:9759064] Awuh, Jane Atesoh
[Person:9664864] Øvervatn, Aud
[Person:8932349] McMahon, Michael
[Person:5432693] Hayes, John D
[Person:6813954] Johansen, Terje |
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| created | [InstanceEdit:9759062] Rothfels, Karen, 2021-11-29 |
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| journal | J Biol Chem |
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| pages | 22576-91 |
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| pubMedIdentifier | 20452972 |
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| title | p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription |
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| volume | 285 |
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| year | 2010 |
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| (literatureReference) | [RegulationReference:9759126] Negative regulation by 'ub-K420 p-S349 SQSTM1 oligomer:KEAP1:CUL3:RBX1 [cytosol]' p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
[RegulationReference:9759156] Positive gene expression regulation by 'SQSTM1 gene: p-NFE2L2:MAFG [nucleoplasm]' p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
[Reaction:9759147] NFE2L2 and MAFG bind the SQSTM1 gene [Homo sapiens]
[BlackBoxEvent:9759157] NFE2L2-dependent SQSTM1 gene expression [Homo sapiens]
[Reaction:9759169] p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 [Homo sapiens]
[BlackBoxEvent:9766656] RBX1:CUL3 dissociates from forming autophagosome [Homo sapiens]
[Complex:9759102] SQSTM1 gene: p-NFE2L2:MAFG [nucleoplasm] [Homo sapiens] |
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