Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Addition of a GlcNAc on the alpha 1,4 branch by MGAT2

Class:Id	Reaction:975829
_displayName	Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
_doRelease	TRUE
_timestamp	2016-11-22 18:39:58
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:975825] alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity of MGAT2 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:975827] Jassal, B, 2010-10-04
edited	[InstanceEdit:975827] Jassal, B, 2010-10-04
input	[SimpleEntity:975819] (GlcNAc)3 (Man)3 (Asn)1 [Golgi lumen] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:1015715] Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development [LiteratureReference:1015735] The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein [LiteratureReference:1015729] Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa
modified	[InstanceEdit:1008193] Jassal, B, 2010-11-10 [InstanceEdit:1015777] Jassal, B, 2010-11-15 [InstanceEdit:1022097] Jassal, B, 2010-11-17 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1028800] Jassal, B, 2010-11-18 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8949380] D'Eustachio, Peter, 2016-11-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
output	[SimpleEntity:975822] (GlcNAc)4 (Man)3 (Asn)1 [Golgi lumen] [SimpleEntity:205687] UDP [Golgi lumen]
precedingEvent	[Reaction:975814] Trimming of mannoses on the alpha1,6 arm by MAN2A1 [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105348] R-HSA-975829.3
summation	[Summation:1015746] The addition of a GlcNAc on the alpha-1,6 mannose on the alp...
(hasEvent)	[Pathway:975578] Reactions specific to the complex N-glycan synthesis pathway [Homo sapiens]
(normalReaction)	[FailedReaction:4793955] Defective MGAT2 does not transfer GlcNAc to N-glycans [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781943] Update Tracker - [Reaction:975829] Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 - v60:[addOutput] [_UpdateTracker:9785923] Update Tracker - [Reaction:975829] Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 - v51:[modifyText] [_UpdateTracker:9786893] Update Tracker - [Reaction:975829] Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 - v47:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (975829)