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Details on Person p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene

Class:Id	Reaction:9756964
_displayName	p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene
_doRelease	TRUE
_timestamp	2022-08-06 03:04:17
authored	[InstanceEdit:9756753] May, Bruce, 2021-10-18
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9756953] May, Bruce, 2021-10-22
edited	[InstanceEdit:9756753] May, Bruce, 2021-10-18
input	[Complex:9756959] Foxh1:Smad3:Gsc gene [nucleoplasm] [Mus musculus] [Complex:9625501] p-2S-Smad2/3:Smad4 [nucleoplasm] [Mus musculus] [Complex:9760357] p-2S-Smad2,3:Trim33 [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9756934] Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling [LiteratureReference:9794953] The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells [LiteratureReference:9756932] A poised chromatin platform for TGF-β access to master regulators [LiteratureReference:2975839] Pluripotency factors regulate definitive endoderm specification through eomesodermin [LiteratureReference:9754504] Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state
modified	[InstanceEdit:9760369] May, Bruce, 2021-12-16 [InstanceEdit:9773647] May, Bruce, 2022-05-08 [InstanceEdit:9794984] May, Bruce, 2022-07-25 [InstanceEdit:9795001] May, Bruce, 2022-07-25 [InstanceEdit:9795002] May, Bruce, 2022-07-25 [InstanceEdit:9796184] May, Bruce, 2022-08-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene
output	[Complex:9756960] p-2S-Smad2,3:Smad4:p-2S-Smad2,3:Trim33:Foxh1:Smad3:Gsc gene [nucleoplasm] [Mus musculus]
releaseDate	2022-06-09
reviewed	[InstanceEdit:9773645] Tam, Patrick P L, 2022-05-08 [InstanceEdit:9794593] Probst, Simone, 2022-07-18 [InstanceEdit:9796183] Zissel, Lea, 2022-07-18 [InstanceEdit:9796182] Salehin, Nazmus, 2022-05-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9756973] R-MMU-9756964.3
summation	[Summation:9760361] In mesendoderm progenitors, Foxh1 and Smad3 are pre-bound to...
(inferredFrom)	[Reaction:9756948] p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9847065] Update Tracker - [Reaction:9756964] p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene - v82:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene (9756964)