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Details on Person EOMES and TBXT bind the POU5F1 (OCT4) gene

Class:Id	Reaction:9756670
_displayName	EOMES and TBXT bind the POU5F1 (OCT4) gene
_doRelease	TRUE
_timestamp	2022-08-06 02:53:50
authored	[InstanceEdit:9756468] May, Bruce, 2021-10-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9756682] May, Bruce, 2021-10-16
edited	[InstanceEdit:9756468] May, Bruce, 2021-10-14
inferredFrom	[Reaction:9756684] Eomes and Tbxt bind the Pou5f1 (Oct4) gene [Mus musculus]
input	[EntityWithAccessionedSequence:452232] EOMES [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:2888984] POU5F1 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452976] TBXT [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9760369] May, Bruce, 2021-12-16 [InstanceEdit:9760419] May, Bruce, 2021-12-18 [InstanceEdit:9773647] May, Bruce, 2022-05-08 [InstanceEdit:9795002] May, Bruce, 2022-07-25 [InstanceEdit:9796184] May, Bruce, 2022-08-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EOMES and TBXT bind the POU5F1 (OCT4) gene
output	[Complex:9756663] EOMES:TBXT:POU5F1 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:452353] Expression of EOMES in the primitive streak [Homo sapiens] [Reaction:9754480] p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene [Homo sapiens] [BlackBoxEvent:452331] Expression of TBXT (T, Brachyury) in the primitive streak [Homo sapiens] [Reaction:9754191] LEF1 or TCF7 (TCF1), CTNNB1, and TBPL2 (TRF3) bind the TBXT (T, Brachyury) gene [Homo sapiens]
releaseDate	2022-06-09
reviewed	[InstanceEdit:9773645] Tam, Patrick P L, 2022-05-08 [InstanceEdit:9794593] Probst, Simone, 2022-07-18 [InstanceEdit:9796183] Zissel, Lea, 2022-07-18 [InstanceEdit:9796182] Salehin, Nazmus, 2022-05-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9756686] R-HSA-9756670.3
summation	[Summation:9760355] EOMES and TBXT bind and repress the expression of POU5F1 (OC...
(hasEvent)	[Pathway:9754189] Germ layer formation at gastrulation [Homo sapiens]
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No pathways have been reviewed or authored by EOMES and TBXT bind the POU5F1 (OCT4) gene (9756670)