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Details on Person Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity
| Class:Id | LiteratureReference:9755753 |
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| _displayName | Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity |
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| _timestamp | 2021-10-11 05:49:52 |
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| author | [Person:8863344] Wang, Shuai
[Person:9755759] Dai, Tong
[Person:9755735] Qin, Ziran
[Person:9683267] Pan, Ting
[Person:9755728] Chu, Feng
[Person:9755754] Lou, Lingfeng
[Person:3009205] Zhang, Long
[Person:5626895] Yang, Bing
[Person:9755730] Huang, Huizhe
[Person:9755750] Lu, Huasong
[Person:9755738] Zhou, Fangfang |
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| created | [InstanceEdit:9755755] Shamovsky, Veronica, 2021-10-11 |
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| journal | Nat Cell Biol |
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| pages | 718-732 |
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| pubMedIdentifier | 34239064 |
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| title | Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity |
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| volume | 23 |
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| year | 2021 |
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| (literatureReference) | [Reaction:9694455] SUMO-p-N protein dimer binds genomic RNA [Homo sapiens]
[Reaction:9755747] SARS-CoV-2 N binds MAVS [Homo sapiens]
[Reaction:9756494] CREBBP acetylates SARS-CoV-2 N at K375 [Homo sapiens]
[Complex:9755729] N:MAVS [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9756489] SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] [Severe acute respiratory syndrome coronavirus 2]
[RegulationReference:9756488] Negative regulation by 'SUMO1-K62,ADPr-,p-11S,2T,met-2R,Ac-K375-N dimer [cytosol]' Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity
[CatalystActivityReference:9756498] peptide-lysine-N-acetyltransferase activity of CREBBP [cytosol] Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity
[Summation:9755752] SARS-CoV-2 nucleocapsid protein (N) can undergo liquid-liqui...
[Summation:9756241] Viral RNA binding to SARS-CoV-2 nucleocapsid protein (N) ind...
[Summation:9756251] Several studies showed that viral RNA binding to SARS-CoV-2 ... |
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