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Details on Person SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix

Class:IdReaction:9754929
_displayNameSLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix
_doReleaseTRUE
_timestamp2022-06-25 07:25:35
authored[InstanceEdit:9755068] Stephan, Ralf, 2021-09-20
catalystActivity[CatalystActivity:9754975] nucleoside transmembrane transporter activity of SLC29A3 [mitochondrial outer membrane]
compartment[Compartment:70101] cytosol
[Compartment:5460] mitochondrial matrix
[Compartment:17906] mitochondrial outer membrane
created[InstanceEdit:9755067] Stephan, Ralf, 2021-10-05
edited[InstanceEdit:9767894] Stephan, Ralf, 2022-03-02
input[DefinedSet:9754954] RBV,RBV-TP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9755034] Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3
[LiteratureReference:9755049] Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3)
[LiteratureReference:9761929] Mitochondrial toxicity is associated with virological response in patients with HIV and hepatitis C virus coinfection treated with ribavirin and highly active antiretroviral therapy
modified[InstanceEdit:9755119] Stephan, Ralf, 2021-10-05
[InstanceEdit:9761238] Stephan, Ralf, 2022-01-11
[InstanceEdit:9761926] Stephan, Ralf, 2022-01-17
[InstanceEdit:9767893] Stephan, Ralf, 2022-03-02
[InstanceEdit:9773825] Stephan, Ralf, 2022-05-10
[InstanceEdit:9773915] Matthews, Lisa, 2022-05-11
[InstanceEdit:9793977] Stephan, Ralf, 2022-06-25
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix
SLC29A3 imports RBV,RBV-TP to mitochondria
output[DefinedSet:9754996] RBV,RBV-TP [mitochondrial matrix]
precedingEvent
releaseDate2022-09-14
reviewed[InstanceEdit:9793976] Thorn, Caroline, 2022-06-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9755113] R-HSA-9754929.2
summation[Summation:9755001] Equilibrative nucleoside transporter 3 (ENT3, SLC29A3) is an...
(hasEvent)[Pathway:9755088] Ribavirin ADME [Homo sapiens]
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