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Details on Person Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

Class:IdLiteratureReference:9750110
_displayNamePre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine
_timestamp2021-08-09 18:50:32
author[Person:6786135] Hartley, John A
[Person:9750113] Flynn, Michael J
[Person:9750115] Bingham, John P
[Person:9736467] Corbett, Simon
[Person:9750111] Reinert, Halla
[Person:9750112] Tiberghien, Arnaud
[Person:9736505] Masterson, Luke A
[Person:9750114] Antonow, Dyeison
[Person:9750119] Adams, Lauren
[Person:9750109] Chowdhury, Sajidah
[Person:9736498] Williams, David G
[Person:9750116] Mao, Shenlan
[Person:9750123] Harper, Jay
[Person:9750117] Havenith, Carin E G
[Person:9750122] Zammarchi, Francesca
[Person:9750120] Chivers, Simon
[Person:9750118] van Berkel, Patrick H
[Person:9736471] Howard, Philip W
created[InstanceEdit:9750121] Orlic-Milacic, Marija, 2021-08-09
journalSci Rep
pages10479
pubMedIdentifier29992976
titlePre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine
volume8
year2018
(literatureReference)[BlackBoxEvent:9713785] Anti-cancer drugs generate DNA interstrand crosslinks [Homo sapiens]
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