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Details on Person CTD1-mediated formation of MCM2-7 double hexamers at the replication origins in budding yeast

Class:IdReaction:9749401
_displayNameCTD1-mediated formation of MCM2-7 double hexamers at the replication origins in budding yeast
_doReleaseTRUE
_timestamp2021-11-10 11:33:54
authored[InstanceEdit:9757622] Kusic-Tisma, Jelena, 2021-10-27
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9749403] Orlic-Milacic, Marija, 2021-08-02
edited[InstanceEdit:9757621] Orlic-Milacic, Marija, 2021-11-03
input[Complex:9749382] yORC(1-6):yCDC6:origin of replication:yMCM2-7 [nucleoplasm] [Saccharomyces cerevisiae]
[Complex:9749307] yCDT1:yMCM2-7 [nucleoplasm] [Saccharomyces cerevisiae]
isChimericFALSE
literatureReference[LiteratureReference:9749309] An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly
[LiteratureReference:8984656] Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing
modified[InstanceEdit:9749411] Orlic-Milacic, Marija, 2021-08-02
[InstanceEdit:9757626] Orlic-Milacic, Marija, 2021-11-03
[InstanceEdit:9758283] Orlic-Milacic, Marija, 2021-11-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCTD1-mediated formation of MCM2-7 double hexamers at the replication origins in budding yeast
output[Complex:9749407] yORC(1-6):yCDC6:origin of replication:yMCM2-7 double hexamer [nucleoplasm] [Saccharomyces cerevisiae]
[EntityWithAccessionedSequence:9749306] yCDT1 [nucleoplasm] [Saccharomyces cerevisiae]
releaseDate2021-12-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:68322] Saccharomyces cerevisiae
stableIdentifier[StableIdentifier:9749404] R-SCE-9749401.2
summation[Summation:9749402] Based on studies in budding yeast, after CDT1-mediated loadi...
(inferredFrom)[Reaction:9749351] CDT1-mediated formation of MCM2-7 double hexamer at the replication origin [Homo sapiens]
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