Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Six homologous minichromosome maintenance proteins, MCM2, MC...
| Class:Id | Summation:9749274 |
|---|---|
| _displayName | Six homologous minichromosome maintenance proteins, MCM2, MC... |
| _timestamp | 2021-07-31 14:17:42 |
| created | [InstanceEdit:9749273] Orlic-Milacic, Marija, 2021-07-31 |
| text | Six homologous minichromosome maintenance proteins, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7, form the evolutionarily conserved MCM2-7 complex, which functions as the core eukaryotic replicated DNA helicase. The structure of the complex is conserved from yeast (Li et al. 2015) to humans (Boskovic et al. 2016), representing an open hexameric ring, with a gate between subunits MCM2 and MCM5. The gate is thought to close and open the MCM2-7 ring to encircle DNA. Each MCM subunit contains an N-terminal DNA interacting and assembly domain and a C-terminal ATP-binding domain. |
| (summation) | [Reaction:9749253] Formation of MCM2-7 complex [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Six homologous minichromosome maintenance proteins, MCM2, MC... (9749274)
