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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person MCM8 binds CDC6

Class:IdReaction:9749215
_displayNameMCM8 binds CDC6
_doReleaseTRUE
_timestamp2021-11-03 15:20:32
authored[InstanceEdit:9757623] Kusic-Tisma, Jelena, 2021-07-31
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9749222] Orlic-Milacic, Marija, 2021-07-31
edited[InstanceEdit:9757621] Orlic-Milacic, Marija, 2021-11-03
input[EntityWithAccessionedSequence:68542] CDC6 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:3006646] MCM8 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:176943] Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin
[LiteratureReference:9749223] MCM8 is regulated by EGFR signaling and promotes the growth of glioma stem cells through its interaction with DNA-replication-initiating factors
modified[InstanceEdit:9749232] Orlic-Milacic, Marija, 2021-07-31
[InstanceEdit:9757621] Orlic-Milacic, Marija, 2021-11-03
[InstanceEdit:9757625] Orlic-Milacic, Marija, 2021-11-03
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMCM8 binds CDC6
output[Complex:9749213] CDC6:MCM8 [nucleoplasm] [Homo sapiens]
releaseDate2021-12-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9749226] R-HSA-9749215.2
summation[Summation:9749231] MCM8, a member of the MCM family of proteins, forms a comple...
(hasEvent)[Pathway:68689] CDC6 association with the ORC:origin complex [Homo sapiens]
[Pathway:9734667] (NEW) Assembly of the ORC complex at the origin of replication [Homo sapiens]
(precedingEvent)[Reaction:68688] CDC6 association with ORC(1-6) at replication origins [Homo sapiens]
[Reaction:9749220] CDC6 binds ORC(1-6) [Homo sapiens]
(replacementInstances)[_Deleted:9768309] Deletion of instance: 176973
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No pathways have been reviewed or authored by MCM8 binds CDC6 (9749215)