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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person Diagram of Azathioprine ADME

Class:IdPathwayDiagram:9749025
_displayNameDiagram of Azathioprine ADME
_timestamp2022-03-10 16:11:54
created[InstanceEdit:9749026] Jassal, Bijay, 2021-07-29
height788
modified[InstanceEdit:9749034] Jassal, Bijay, 2021-07-29
[InstanceEdit:9749711] Jassal, Bijay, 2021-08-04
[InstanceEdit:9750269] Jassal, Bijay, 2021-08-11
[InstanceEdit:9750573] Jassal, Bijay, 2021-08-16
[InstanceEdit:9750967] Jassal, Bijay, 2021-08-17
[InstanceEdit:9751031] Jassal, Bijay, 2021-08-17
[InstanceEdit:9751199] Jassal, Bijay, 2021-08-19
[InstanceEdit:9751218] Jassal, Bijay, 2021-08-20
[InstanceEdit:9755271] Jassal, Bijay, 2021-10-07
[InstanceEdit:9758051] Jassal, Bijay, 2021-11-09
[InstanceEdit:9758444] Jassal, Bijay, 2021-11-12
[InstanceEdit:9758494] Matthews, Lisa, 2021-11-15
[InstanceEdit:9758643] Matthews, Lisa, 2021-11-22
[InstanceEdit:9768365] Matthews, Lisa, 2022-03-10
[InstanceEdit:9768367] Wu, Guanming, 2022-03-10
representedPathway[Pathway:9748787] Azathioprine ADME [Homo sapiens]
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<Properties> <displayName>TPMT transfers methyl group to 6TIMP, forming 6MeTIMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="222" reactomeId="9748983" points="515 409, 515 370, 515 335" position="515 370" lineWidth="1.0"> <Inputs> <Input id="252" points="515 452" /> <Input id="269" points="538 417" /> </Inputs> <Outputs> <Output id="221" points="515 268" /> <Output id="214" points="498 326" /> <Output id="262" points="539 328" /> </Outputs> <Catalysts> <Catalyst id="258" points="555 369" /> </Catalysts> <Properties> <displayName>TPMT transfers methyl group to 6MP, forming 6MeMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="228" reactomeId="9748945" points="966 470, 1012 470, 1068 470" position="1012 470" lineWidth="1.0"> <Inputs> <Input id="226" points="929 499" /> <Input id="260" points="962 491" /> <Input id="238" points="909 470" /> </Inputs> <Outputs> <Output id="220" points="1086 490" /> <Output id="241" points="1136 470" /> <Output id="259" points="1087 451" /> </Outputs> <Catalysts> <Catalyst id="219" points="1012 536" /> </Catalysts> <Properties> <displayName>IMPDH tetramers dehydrogenate 6TIMP to 6TXMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="231" reactomeId="9748949" points="1589 471, 1636 471, 1680 471" position="1636 471" lineWidth="1.0"> <Inputs> <Input id="251" points="1551 471" /> <Input id="309" points="1576 451" /> </Inputs> <Outputs> <Output id="242" points="1718 471" /> <Output id="313" points="1690 447" /> </Outputs> <Catalysts> <Catalyst id="417" points="1636 521" /> </Catalysts> <Properties> <displayName>GUK1 phosphorylates 6TGMP to 6TGDP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="232" reactomeId="9748951" points="677 470, 728 470, 775 470" position="728 470" lineWidth="1.0"> <Inputs> <Input id="252" points="539 470" /> <Input id="239" points="660 482" /> </Inputs> <Outputs> <Output id="238" points="850 470" /> <Output id="271" points="791 487" /> </Outputs> <Catalysts> <Catalyst id="233" points="728 437" /> </Catalysts> <Properties> <displayName>HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="235" reactomeId="9748991" points="515 560, 515 602, 515 641" position="515 602" lineWidth="1.0"> <Inputs> <Input id="2034" stoichiometry="2" points="485 547" /> <Input id="252" points="515 489" /> <Input id="652" stoichiometry="2" points="548 546" /> </Inputs> <Outputs> <Output id="217" points="515 695" /> <Output id="650" stoichiometry="2" points="569 669" /> <Output id="654" stoichiometry="2" points="468 665" /> </Outputs> <Catalysts> <Catalyst id="236" points="557 602" /> </Catalysts> <Properties> <displayName>XDH oxidises 6MP to 6TU</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="240" reactomeId="9748957" points="1271 471, 1326 471, 1393 471" position="1326 471" lineWidth="1.0"> <Inputs> <Input id="241" points="1200 471" /> <Input id="243" points="1256 528" /> <Input id="227" points="1199 508" /> <Input id="256" points="1239 501" /> </Inputs> <Outputs> <Output id="212" points="1398 510" /> <Output id="246" points="1435 528" /> <Output id="237" points="1474 532" /> <Output id="251" points="1486 471" /> <Output id="264" stoichiometry="2" points="1464 502" /> </Outputs> <Catalysts> <Catalyst id="655" points="1326 501" /> </Catalysts> <Properties> <displayName>GMPS dimer transforms 6TXMP to 6TGMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="250" reactomeId="9748996" points="262 469, 310 469, 353 469" position="310 469" lineWidth="1.0"> <Inputs> <Input id="245" points="210 469" /> <Input id="215" points="257 491" /> </Inputs> <Outputs> <Output id="216" points="372 488" /> <Output id="252" points="491 469" /> </Outputs> <Catalysts> <Catalyst id="255" points="310 439" /> </Catalysts> <Properties> <displayName>GST dimers cleave AZA to 6MP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="253" reactomeId="9748999" points="1828 471, 1881 471, 1929 471" position="1881 471" lineWidth="1.0"> <Inputs> <Input id="242" points="1782 471" /> <Input id="311" points="1805 447" /> </Inputs> <Outputs> <Output id="230" points="2001 471" /> <Output id="254" points="1954 450" /> </Outputs> <Catalysts> <Catalyst id="411" points="1882 510" /> </Catalysts> <Properties> <displayName>NME1:2 hexamer phosphorylates 6TGDP to 6TGTP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="399" reactomeId="9748963" points="1544 602, 1584 602, 1628 602" position="1584 602" lineWidth="1.0"> <Inputs> <Input id="400" points="1501 602" /> <Input id="401" points="1524 618" /> </Inputs> <Outputs> <Output id="402" points="1683 602" /> <Output id="403" points="1645 623" /> </Outputs> <Catalysts> <Catalyst id="417" points="1627 550" /> </Catalysts> <Properties> <displayName>GUK1 phosphorylates 6TdGMP to 6TdGDP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="413" reactomeId="9748969" points="1812 603, 1883 603, 1954 603" position="1883 603" lineWidth="1.0"> <Inputs> <Input id="414" points="1793 624" /> <Input id="402" points="1755 603" /> </Inputs> <Outputs> <Output id="415" points="2014 603" /> <Output id="416" points="1969 622" /> </Outputs> <Catalysts> <Catalyst id="411" points="1883 553" /> </Catalysts> <Properties> <displayName>NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="981" reactomeId="9750555" points="1977 693, 1761 693, 1478 693" position="1761 693" lineWidth="1.0"> <Inputs> <Input id="415" points="2036 622" /> <Input id="982" points="1989 715" /> </Inputs> <Outputs> <Output id="400" points="1466 622" /> <Output id="985" points="1454 715" /> </Outputs> <Catalysts> <Catalyst id="983" points="1761 726" /> </Catalysts> <Properties> <displayName>NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1097" reactomeId="9750617" points="1408 212, 1408 181, 1408 181" position="1408 181" lineWidth="1.0"> <Inputs> <Input id="1098" points="1388 228" /> <Input id="1099" points="1408 304" /> <Input id="1104" points="1342 229" /> </Inputs> <Outputs> <Output id="1105" points="1449 216" /> <Output id="1106" points="1486 206" /> <Output id="1107" points="1408 109" /> </Outputs> <Catalysts> <Catalyst id="1108" points="1366 180" /> </Catalysts> <Properties> <displayName>ABCC5 transports TPMP substrates from cytosol to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="1100" points="918 247, 1359 320" position="1138 283" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="223" /> </Inputs> <Outputs> <Output id="1099" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1101" points="1505 454, 1423 353" position="1464 403" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="251" /> </Inputs> <Outputs> <Output id="1099" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1102" points="1195 453, 1377 353" position="1286 403" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="241" /> </Inputs> <Outputs> <Output id="1099" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1103" points="909 463, 1359 339" position="1134 401" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="238" /> </Inputs> <Outputs> <Output id="1099" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="1155" reactomeId="9750546" points="1081 218, 1081 181, 1081 180" position="1081 181" lineWidth="1.0"> <Inputs> <Input id="1156" points="1018 230" /> <Input id="1157" points="1081 299" /> <Input id="1162" points="1064 228" /> </Inputs> <Outputs> <Output id="1163" points="1081 107" /> <Output id="1165" points="1203 220" /> <Output id="1167" points="1145 222" /> </Outputs> <Catalysts> <Catalyst id="1166" points="1044 181" /> </Catalysts> <Properties> <displayName>ABCC4 transports TPMP substrates from cytosol to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="1158" points="918 256, 1032 305" position="975 280" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="223" /> </Inputs> <Outputs> <Output id="1157" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1159" points="1486 461, 1132 338" position="1309 399" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="251" /> </Inputs> <Outputs> <Output id="1157" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1160" points="901 453, 1056 348" position="978 400" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="238" /> </Inputs> <Outputs> <Output id="1157" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="1648" reactomeId="9751051" points="110 78, 158 78, 195 78" position="158 78" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="1649" points="54 78" /> <Input id="1650" points="81 48" /> </Inputs> <Outputs> <Output id="1651" points="252 78" /> <Output id="1652" points="229 49" /> </Outputs> <Properties> <displayName>GSH cleaves AZA to 6MP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1788" reactomeId="9751037" points="219 154, 219 180, 219 217" position="219 180" lineWidth="1.0"> <Inputs> <Input id="1789" points="204 140" /> <Input id="1651" points="264 97" /> </Inputs> <Outputs> <Output id="1790" points="196 238" /> <Output id="252" points="496 452" /> </Outputs> <Catalysts> <Catalyst id="1791" points="186 180" /> </Catalysts> <Properties> <displayName>SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1792" reactomeId="9751024" points="275 97, 275 180, 502 452" position="275 180" lineWidth="1.0"> <Inputs> <Input id="1651" /> </Inputs> <Outputs> <Output id="252" /> </Outputs> <Catalysts> <Catalyst id="1793" points="336 180" /> </Catalysts> <Properties> <displayName>SLC29A1,2 transport 6MP from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1937" reactomeId="9751201" points="2218 402, 2218 432, 2218 490" position="2218 432" lineWidth="1.0"> <Inputs> <Input id="1938" points="2218 364" /> <Input id="230" points="2047 454, 2146 358" /> </Inputs> <Outputs> <Output id="1939" points="2185 507" /> <Output id="1940" points="2218 535" /> </Outputs> <Catalysts> <Catalyst id="1942" points="2186 431" /> </Catalysts> <Properties> <displayName>p-VAV1,2,3 exchange 6TGTP for GDP on RAC1</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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No pathways have been reviewed or authored by Diagram of Azathioprine ADME (9749025)
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