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Details on Person GUK1 phosphorylates 6TGMP to 6TGDP

Class:Id	Reaction:9748949
_displayName	GUK1 phosphorylates 6TGMP to 6TGDP
_doRelease	TRUE
_timestamp	2021-10-19 12:35:36
authored	[InstanceEdit:9748997] Jassal, Bijay, 2021-07-29
catalystActivity	[CatalystActivity:74189] GMP kinase activity of GUK1 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9748997] Jassal, Bijay, 2021-07-29
edited	[InstanceEdit:9748997] Jassal, Bijay, 2021-07-29
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
input	[SimpleEntity:9748970] 6TGMP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:110117] Guanylate kinases from human erythrocytes, hog brain, and rat liver [LiteratureReference:9749708] Reassessment of the interactions of guanylate kinase and 6-thioguanosine 5'-phosphate
modified	[InstanceEdit:9749711] Jassal, Bijay, 2021-08-04 [InstanceEdit:9749777] Jassal, Bijay, 2021-08-05 [InstanceEdit:9755271] Jassal, Bijay, 2021-10-07 [InstanceEdit:9756882] Jassal, Bijay, 2021-10-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GUK1 phosphorylates 6TGMP to 6TGDP 6TGMP--MPK-->6TGDP
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:9748960] 6TGDP [cytosol]
precedingEvent	[Reaction:9748957] GMPS dimer transforms 6TXMP to 6TGMP [Homo sapiens] [Reaction:9748945] IMPDH tetramers dehydrogenate 6TIMP to 6TXMP [Homo sapiens]
releaseDate	2021-12-08
reviewed	[InstanceEdit:9756856] Huddart, Rachel, 2021-10-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9749019] R-HSA-9748949.2
summation	[Summation:9749709] 6-thioguanine nucleotides (6-TGNs) consist of 6-thio(deoxy)g...
(hasEvent)	[Pathway:9748787] Azathioprine ADME [Homo sapiens]
(precedingEvent)	[Reaction:9748999] NME1:2 hexamer phosphorylates 6TGDP to 6TGTP [Homo sapiens]
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No pathways have been reviewed or authored by GUK1 phosphorylates 6TGMP to 6TGDP (9748949)