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Details on Person After initial activation of NKX2-5 and GATA4 by MESP1, GATA4...
| Class:Id | Summation:9748878 |
|---|---|
| _displayName | After initial activation of NKX2-5 and GATA4 by MESP1, GATA4... |
| _timestamp | 2021-08-06 10:51:08 |
| created | [InstanceEdit:9748891] May, Bruce, 2021-07-28 |
| modified | [InstanceEdit:9749852] May, Bruce, 2021-08-06 |
| text | After initial activation of NKX2-5 and GATA4 by MESP1, GATA4 binds the promoter of the NKX2-5 gene and activates transcription (inferred from mouse homologs). SMAD1:SMAD4 complexes that are apparently activated by BMP signaling also bind the NKX2-5 promoter, recruit GATA4, and synergistically enhance transcription (inferred from mouse homologs). TBX20 binds the cardiac enhancer of the NKX2-5 promoter and activates transcription (inferred from mouse homologs) |
| (summation) | [Reaction:9734353] GATA4, SMAD1:SMAD4, MEF2C, TBX20, and NKX2-5 bind the NKX2-5 gene [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by After initial activation of NKX2-5 and GATA4 by MESP1, GATA4... (9748878)
