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Details on Person CRL1 (BTRC) polyubiquitinates NLRP3 at K384

Class:IdBlackBoxEvent:9748776
_displayNameCRL1 (BTRC) polyubiquitinates NLRP3 at K384
_doReleaseFALSE
_timestamp2022-06-09 23:17:11
catalystActivity[CatalystActivity:9750236] ubiquitin protein ligase activity of K27polyUb-384-NLRP3:BTRC:CUL1:RBX1:SKP1 [cytosol]
catalystActivityReference[CatalystActivityReference:9750238] ubiquitin protein ligase activity of K27polyUb-384-NLRP3:BTRC:CUL1:RBX1:SKP1 [cytosol] YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
compartment[Compartment:70101] cytosol
created[InstanceEdit:9748770] Shamovsky, Veronica, 2021-07-27
input[EntityWithAccessionedSequence:561189] NLRP3 [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[Complex:206748] BTRC:CUL1:RBX1:SKP1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9748775] YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
modified[InstanceEdit:9750237] Shamovsky, Veronica, 2021-08-11
[InstanceEdit:9792815] Shamovsky, Veronica, 2022-05-31
[InstanceEdit:9793149] Shamovsky, Veronica, 2022-06-06
[InstanceEdit:9793287] Shamovsky, Veronica, 2022-06-09
nameCRL1 (BTRC) polyubiquitinates NLRP3 at K384
output[Complex:9750235] K27polyUb-384-NLRP3:BTRC:CUL1:RBX1:SKP1 [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9748782] R-HSA-9748776.1
summation[Summation:9748780] F-box/WD repeat-containing protein 1A (also known as β-trans...
(hasEvent)[Pathway:9712312] Regulation of NLRP3 inflammasome [Homo sapiens]
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No pathways have been reviewed or authored by CRL1 (BTRC) polyubiquitinates NLRP3 at K384 (9748776)
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