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Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P54784 ORC1
Class:Id
ReferenceGeneProduct:97388
_chainChangeLog
chain:1-914 added on Fri February 6 2015
_displayName
UniProt:P54784 ORC1
_timestamp
2023-11-03 15:50:35
chain
chain:1-914
checksum
BDAA9D3E40B4B76A
comment
FUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. Interacts with MCM10 and TAH11.INTERACTION The N-terminus is dedicated to mating-type repression.MISCELLANEOUS Present with 3930 molecules/cell in log phase SD medium.SIMILARITY Belongs to the ORC1 family.
3D-structure ATP-binding Direct protein sequencing DNA replication DNA-binding Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome
