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Details on Person SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter

Class:Id	Reaction:9737710
_displayName	SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter
_doRelease	TRUE
_timestamp	2024-05-16 04:32:08
authored	[InstanceEdit:9692648] Shamovsky, Veronica, 2020-06-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9737697] Shamovsky, Veronica, 2021-07-21
disease	[Disease:9678120] severe acute respiratory syndrome
edited	[InstanceEdit:9796665] Shamovsky, Veronica, 2022-08-11
input	[Complex:8878153] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:1592223] SP1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:2106592] SERPINE1 gene [nucleoplasm] [Homo sapiens] [Complex:9683761] SUMO-p-N dimer [nucleolus] [Human SARS coronavirus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9727871] Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signaling
modified	[InstanceEdit:9796162] Shamovsky, Veronica, 2022-08-05 [InstanceEdit:9796525] Shamovsky, Veronica, 2022-08-10 [InstanceEdit:9796657] Shamovsky, Veronica, 2022-08-11 [InstanceEdit:9815468] Shamovsky, Veronica, 2022-08-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910650] Shamovsky, Veronica, 2024-05-16
name	SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter
output	[Complex:9737684] SARS-CoV-1 N:p-2S-SMAD3:SP1:EP300:SERPINE1 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:177103] SMAD4 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9683606] Nucleoprotein translocates to the nucleolus [Homo sapiens] [Reaction:9683634] Dimerisation of nucleoprotein [Homo sapiens]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-09-14
reviewed	[InstanceEdit:9713569] D'Eustachio, Peter, 2021-01-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9737714] R-HSA-9737710.3
summation	[Summation:9737696] Severe acute respiratory syndrome associated coronavirus typ...
(hasEvent)	[Pathway:9735871] SARS-CoV-1 targets host intracellular signalling and regulatory pathways [Homo sapiens]
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No pathways have been reviewed or authored by SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter (9737710)