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Details on Person Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer
| Class:Id | LiteratureReference:9736055 |
|---|---|
| _displayName | Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer |
| _timestamp | 2021-07-06 12:53:11 |
| author | [Person:9736164] Jia, Hong [Person:9736282] Dai, Guangxiu [Person:9736065] Weng, Jianyang [Person:9736097] Zhang, Zhulin [Person:2032901] Wang, Q [Person:5654821] Zhou, Feng [Person:9736060] Jiao, Longxian [Person:9736043] Cui, Yumin [Person:9736244] Ren, Yongxin [Person:9736206] Fan, Shiming [Person:9736217] Zhou, Jinghong [Person:9736132] Qing, Weiguo [Person:9649062] Gu, Yi [Person:2684914] Wang, Jian [Person:9736049] Sai, Yang [Person:9736211] Su, Weiguo |
| created | [InstanceEdit:9736264] Orlic-Milacic, Marija, 2021-07-06 |
| journal | J Med Chem |
| pages | 7577-89 |
| pubMedIdentifier | 25148209 |
| title | Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer |
| volume | 57 |
| year | 2014 |
| (literatureReference) | [Reaction:9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Homo sapiens] |
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No pathways have been reviewed or authored by Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer (9736055)
