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Details on Person Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily

Class:Id	LiteratureReference:9736044
_displayName	Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily
_timestamp	2021-07-06 12:53:09
author	[Person:9736122] Schroeder, Gretchen M [Person:9736015] An, Yongmi [Person:9736016] Cai, Zhen-Wei [Person:9736140] Chen, Xiao-Tao [Person:9736010] Clark, Cheryl [Person:9674201] Cornelius, Lyndon A M [Person:9736207] Dai, Jun [Person:9656477] Gullo-Brown, Johnni [Person:9736272] Gupta, Ashok [Person:9736227] Henley, Benjamin [Person:9656475] Hunt, John T [Person:9736121] Jeyaseelan, Robert [Person:9674208] Kamath, Amrita [Person:9736188] Kim, Kyoung [Person:9736036] Lippy, Jonathan [Person:9674207] Lombardo, Louis J [Person:6801130] Manne, Veeraswamy [Person:9736091] Oppenheimer, Simone [Person:9736257] Sack, John S [Person:9624557] Schmidt, Robert J [Person:9736154] Shen, Guoxiang [Person:9736283] Stefanski, Kevin [Person:9736254] Tokarski, John S [Person:9736078] Trainor, George L [Person:9736269] Wautlet, Barri S [Person:9736266] Wei, Donna [Person:9736214] Williams, David K [Person:9736117] Zhang, Yingru [Person:9736127] Zhang, Yueping [Person:2077323] Fargnoli, J [Person:9674199] Borzilleri, Robert M
created	[InstanceEdit:9736264] Orlic-Milacic, Marija, 2021-07-06
journal	J Med Chem
pages	1251-4
pubMedIdentifier	19260711
title	Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily
volume	52
year	2009
(literatureReference)	[Reaction:9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Homo sapiens]
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No pathways have been reviewed or authored by Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily (9736044)