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Details on Person GATA4 and NKX2-5 bind the HAND1 gene

Class:Id	Reaction:9735268
_displayName	GATA4 and NKX2-5 bind the HAND1 gene
_doRelease	TRUE
_timestamp	2023-05-03 20:47:24
authored	[InstanceEdit:9735227] May, Bruce, 2021-06-23
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9735290] May, Bruce, 2021-06-24
edited	[InstanceEdit:9735227] May, Bruce, 2021-06-23
inferredFrom	[Reaction:9795234] Gata4 binds the Hand1 gene [Mus musculus]
input	[EntityWithAccessionedSequence:9735326] HAND1 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:4005994] NKX2-5 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:400553] GATA4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:400553] GATA4 [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9833807] Matthews, Lisa, 2023-05-03
isChimeric	FALSE
literatureReference	[LiteratureReference:9735254] NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network
modified	[InstanceEdit:9749090] May, Bruce, 2021-07-30 [InstanceEdit:9795237] May, Bruce, 2022-08-02 [InstanceEdit:9796185] May, Bruce, 2022-08-06 [InstanceEdit:9796481] May, Bruce, 2022-08-10 [InstanceEdit:9833806] Matthews, Lisa, 2023-05-03
name	GATA4 and NKX2-5 bind the HAND1 gene
output	[Complex:9735301] GATA4:NKX2-5:HAND1 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9733772] Expression of NKX2-5 in cardiogenesis [Homo sapiens] [Reaction:9733744] MESP1 binds the NKX2-5 gene [Homo sapiens] [Reaction:9734353] GATA4, SMAD1:SMAD4, MEF2C, TBX20, and NKX2-5 bind the NKX2-5 gene [Homo sapiens]
releaseDate	2023-06-07
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9735346] R-HSA-9735268.1
summation	[Summation:9749077] NKX2-5 binds the HAND1 (eHAND) gene and activates transcript...
(hasEvent)	[Pathway:9733709] Cardiogenesis [Homo sapiens]
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No pathways have been reviewed or authored by GATA4 and NKX2-5 bind the HAND1 gene (9735268)