Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]' Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Class:IdRegulationReference:9735230
_displayNameNegative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]' Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
_timestamp2021-06-23 13:03:06
created[InstanceEdit:9735231] Jassal, Bijay, 2021-06-23
literatureReference[LiteratureReference:9038770] Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
[LiteratureReference:9015065] Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor
[LiteratureReference:9038773] Edoxaban, a Novel Oral Factor Xa Inhibitor
[LiteratureReference:9603677] Efficacy and toxicity of factor Xa inhibitors
[LiteratureReference:9038767] The new factor Xa inhibitor: Apixaban
regulation[NegativeRegulation:9015052] Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]'
(regulationReference)[Reaction:140700] prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) [Homo sapiens]
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No pathways have been reviewed or authored by Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]' Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor (9735230)
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