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Details on Person SLC51A:SLC51B transports bile salts from cytosol to extracellular region

Class:IdReaction:9733964
_displayNameSLC51A:SLC51B transports bile salts from cytosol to extracellular region
_doReleaseTRUE
_timestamp2021-06-21 12:34:47
authored[InstanceEdit:9733974] Jassal, Bijay, 2021-06-14
catalystActivity[CatalystActivity:9733966] bile acid transmembrane transporter activity of SLC51A:SLC51B [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9733974] Jassal, Bijay, 2021-06-14
edited[InstanceEdit:9733974] Jassal, Bijay, 2021-06-14
input[DefinedSet:194156] bile salts and acids [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9733980] OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
[LiteratureReference:9733977] Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter
modified[InstanceEdit:9735075] Jassal, Bijay, 2021-06-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC51A:SLC51B transports bile salts from cytosol to extracellular region
OSTA:OSTB exports bile salts from enterocytes to the portal system
output[DefinedSet:192483] bile salts and acids [extracellular region]
releaseDate2021-09-15
reviewed[InstanceEdit:9735076] D'Eustachio, Peter, 2021-06-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9733984] R-HSA-9733964.2
summation[Summation:9733967] Bile salt and acid uptake across the apical membrane of ilea...
(hasEvent)[Pathway:159418] Recycling of bile acids and salts [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9733545] Bile salts and acids bind ALB [Homo sapiens]
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