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Details on Person SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
| Class:Id | LiteratureReference:9733465 |
| _displayName | SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation |
| _timestamp | 2021-06-04 21:29:48 |
| author | [Person:9733488] Sanders, David W [Person:9733486] Jumper, Chanelle C [Person:9733459] Ackerman, Paul J [Person:9733510] Bracha, Dan [Person:9733515] Donlic, Anita [Person:9733500] Kim, Hahn [Person:9733461] Kenney, Devin [Person:9733471] Castello-Serrano, Ivan [Person:9733513] Suzuki, Saori [Person:9733506] Tamura, Tomokazu [Person:9733502] Tavares, Alexander H [Person:9733498] Saeed, Mohsan [Person:5696321] Holehouse, Alex S [Person:9733507] Ploss, Alexander [Person:9733464] Levental, Ilya [Person:9733460] Douam, Florian [Person:9733482] Padera, Robert F [Person:8952143] Levy, Bruce D [Person:9733470] Brangwynne, Clifford P |
| created | [InstanceEdit:9733469] Stephan, Ralf, 2021-06-04 |
| journal | Elife |
| pubMedIdentifier | 33890572 |
| title | SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation |
| volume | 10 |
| year | 2021 |
| (literatureReference) | [EntityWithAccessionedSequence:9733472] fully glycosylated Spike [plasma membrane] [Severe acute respiratory syndrome coronavirus 2] [Complex:9733494] S1 trimer:ACE2:S2 trimer [plasma membrane] [Homo sapiens] [Complex:9770062] S1:ACE2 [plasma membrane] [Homo sapiens] [Pathway:9733458] Induction of Cell-Cell Fusion [Homo sapiens] [Reaction:9733495] Viral Spike Binds to ACE2 on Uninfected Cell [Homo sapiens] [Reaction:9770187] S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion [Homo sapiens] |
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No pathways have been reviewed or authored by SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation (9733465)