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Details on Person SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

Class:IdLiteratureReference:9733465
_displayNameSARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
_timestamp2021-06-04 21:29:48
author[Person:9733488] Sanders, David W
[Person:9733486] Jumper, Chanelle C
[Person:9733459] Ackerman, Paul J
[Person:9733510] Bracha, Dan
[Person:9733515] Donlic, Anita
[Person:9733500] Kim, Hahn
[Person:9733461] Kenney, Devin
[Person:9733471] Castello-Serrano, Ivan
[Person:9733513] Suzuki, Saori
[Person:9733506] Tamura, Tomokazu
[Person:9733502] Tavares, Alexander H
[Person:9733498] Saeed, Mohsan
[Person:5696321] Holehouse, Alex S
[Person:9733507] Ploss, Alexander
[Person:9733464] Levental, Ilya
[Person:9733460] Douam, Florian
[Person:9733482] Padera, Robert F
[Person:8952143] Levy, Bruce D
[Person:9733470] Brangwynne, Clifford P
created[InstanceEdit:9733469] Stephan, Ralf, 2021-06-04
journalElife
pubMedIdentifier33890572
titleSARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
volume10
year2021
(literatureReference)[EntityWithAccessionedSequence:9733472] fully glycosylated Spike [plasma membrane] [Severe acute respiratory syndrome coronavirus 2]
[Complex:9733494] S1 trimer:ACE2:S2 trimer [plasma membrane] [Homo sapiens]
[Complex:9770062] S1:ACE2 [plasma membrane] [Homo sapiens]
[Pathway:9733458] Induction of Cell-Cell Fusion [Homo sapiens]
[Reaction:9733495] Viral Spike Binds to ACE2 on Uninfected Cell [Homo sapiens]
[Reaction:9770187] S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion [Homo sapiens]
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No pathways have been reviewed or authored by SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation (9733465)