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Details on Person Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Class:IdLiteratureReference:9733370
_displayNameTherapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
_timestamp2021-06-04 12:50:15
author[Person:9733384] Frank-Kamenetsky, Maria
[Person:9733400] Grefhorst, Aldo
[Person:9621575] Anderson, Norma N
[Person:9733419] Racie, Timothy S
[Person:9733394] Bramlage, Birgit
[Person:9733375] Akinc, Akin
[Person:9733422] Butler, David
[Person:9733420] Charisse, Klaus
[Person:9733372] Dorkin, Robert
[Person:9733423] Fan, Yupeng
[Person:9733395] Gamba-Vitalo, Christina
[Person:3465507] Hadwiger, Philipp
[Person:9733424] Jayaraman, Muthusamy
[Person:9733368] John, Matthias
[Person:9733416] Jayaprakash, K Narayanannair
[Person:9733376] Maier, Martin
[Person:9733379] Nechev, Lubomir
[Person:9733408] Rajeev, Kallanthottathil G
[Person:9733428] Read, Timothy
[Person:9733392] Röhl, Ingo
[Person:9733364] Soutschek, Jürgen
[Person:9733382] Tan, Pamela
[Person:9733421] Wong, Jamie
[Person:8983539] Wang, Gang
[Person:9733389] Zimmermann, Tracy
[Person:9733380] de Fougerolles, Antonin
[Person:3465358] Vornlocher, Hans-Peter
[Person:9733411] Langer, Robert
[Person:9733432] Anderson, Daniel G
[Person:9733381] Manoharan, Muthiah
[Person:8875259] Koteliansky, Victor
[Person:164219] Horton, JD
[Person:2993836] Fitzgerald, Kevin
created[InstanceEdit:9733402] Jassal, Bijay, 2021-06-04
journalProc Natl Acad Sci U S A
pages11915-20
pubMedIdentifier18695239
titleTherapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
volume105
year2008
(literatureReference)[RegulationReference:9733399] Negative gene expression regulation by 'inclisiran [extracellular region]' A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
[RNADrug:9733431] inclisiran [extracellular region]
[Summation:9733387] Low-density lipoprotein (LDL) receptors expressed on hepatoc...
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No pathways have been reviewed or authored by Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates (9733370)