Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person May, Bruce, 2021-06-03

Class:IdInstanceEdit:9733353
_displayNameMay, Bruce, 2021-06-03
_timestamp2021-06-03 19:42:44
author[Person:203835] May, Bruce
dateTime2021-06-03 19:42:42
(modified)[Reaction:389159] CSF1R trans-autophosphorylates on multiple tyrosine and serine residues [Homo sapiens]
[BlackBoxEvent:9680348] PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated [Homo sapiens]
[Pathway:9680350] Signaling by CSF1 (M-CSF) in myeloid cells [Homo sapiens]
[Complex:9680374] CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] [Homo sapiens]
[Reaction:9680385] CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS [Homo sapiens]
[CatalystActivity:9680390] guanyl-nucleotide exchange factor activity of CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane]
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No pathways have been reviewed or authored by May, Bruce, 2021-06-03 (9733353)