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Details on Person CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1

Class:Id	Reaction:9733331
_displayName	CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1
_doRelease	TRUE
_timestamp	2022-10-09 06:41:25
authored	[InstanceEdit:9733318] May, Bruce, 2021-05-25
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9733322] May, Bruce, 2021-06-03
edited	[InstanceEdit:9733318] May, Bruce, 2021-05-25
inferredFrom	[Reaction:9764150] Csf1 dimer:p-Y-559-Csf1r dimer:SFK:Grb2:Sos1 dissociates yielding Csf1 dimer:p-Y-559-Csf1r dimer:SFK and Grb2:Sos1 [Mus musculus]
input	[Complex:9733324] CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9763923] May, Bruce, 2022-02-07 [InstanceEdit:9764153] May, Bruce, 2022-02-09 [InstanceEdit:9766330] May, Bruce, 2022-02-18 [InstanceEdit:9818020] May, Bruce, 2022-10-08 [InstanceEdit:9818021] May, Bruce, 2022-10-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1
output	[Complex:109797] GRB2-1:SOS1 [cytosol] [Homo sapiens] [Complex:9818000] CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9680385] CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS [Homo sapiens] [Reaction:9733330] CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds GRB2:SOS1 [Homo sapiens]
releaseDate	2022-12-07
reviewed	[InstanceEdit:9817996] Stanley, E Richard, 2022-10-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9733348] R-HSA-9733331.2
summation	[Summation:9766321] GRB2:SOS1 transiently associates with phosphorylated CSF1R a...
(hasEvent)	[Pathway:9680350] Signaling by CSF1 (M-CSF) in myeloid cells [Homo sapiens]
(precedingEvent)	[Reaction:9817983] CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL [Homo sapiens]
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No pathways have been reviewed or authored by CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1 (9733331)