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Details on Person EDNRA binds selective ERAs

Class:IdReaction:9731931
_displayNameEDNRA binds selective ERAs
_doReleaseTRUE
_timestamp2022-05-10 17:55:47
authored[InstanceEdit:9724665] Jassal, Bijay, 2021-03-25
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9731928] Jassal, Bijay, 2021-05-25
definitionAntagonist
edited[InstanceEdit:9757169] Jassal, Bijay, 2021-10-27
[InstanceEdit:9773839] Matthews, Lisa, 2022-05-10
input[EntityWithAccessionedSequence:388549] EDNRA [plasma membrane] [Homo sapiens]
[DefinedSet:9731926] selective ERAs [extracellular region]
literatureReference[LiteratureReference:9731389] Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist
[LiteratureReference:9731414] Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists
modified[InstanceEdit:9773229] Matthews, Lisa, 2022-05-03
[InstanceEdit:9773839] Matthews, Lisa, 2022-05-10
[InstanceEdit:9773858] Matthews, Lisa, 2022-05-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEDNRA binds selective ERAs
EDNRA binds selective EDNR antagonists
output[Complex:9731927] EDNRA:selective ERAs [plasma membrane] [Homo sapiens]
reactionType[DrugActionType:9725064] Antagonist
releaseDate2022-06-09
reviewed[InstanceEdit:9767610] Huddart, Rachel, 2022-03-01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9731933] R-HSA-9731931.2
summation[Summation:9731929] Endothelins (EDNs) are 21-amino acid vasoconstricting peptid...
(hasEvent)[Pathway:375276] Peptide ligand-binding receptors [Homo sapiens]
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No pathways have been reviewed or authored by EDNRA binds selective ERAs (9731931)