Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Nucleoprotein is SUMOylated

Class:IdReaction:9729307
_displayNameNucleoprotein is SUMOylated
_doReleaseTRUE
_timestamp2022-04-29 20:04:29
authored[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
compartment[Compartment:70101] cytosol
created[InstanceEdit:9729337] Stephan, Ralf, 2021-04-28
disease[Disease:9683912] COVID-19
edited[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
[InstanceEdit:9730594] Stephan, Ralf, 2021-05-10
inferredFrom
input[Complex:4656922] SUMO1:C93-UBE2I [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9729275] ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2]
isChimericFALSE
literatureReference[LiteratureReference:9682825] Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus
modified[InstanceEdit:9730583] Stephan, Ralf, 2021-05-10
[InstanceEdit:9730592] Stephan, Ralf, 2021-05-10
[InstanceEdit:9730595] Stephan, Ralf, 2021-05-10
[InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNucleoprotein is SUMOylated
output[EntityWithAccessionedSequence:4655342] UBE2I [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2]
precedingEvent
relatedSpecies[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate2020-09-15
reviewed[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
[InstanceEdit:9730585] Acencio, Marcio Luis, 2021-05-09
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9730582] Stephan, Ralf, 2021-05-10
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9729363] R-HSA-9729307.3
summation[Summation:9694340] This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

N protein is sumoylated at a lysine residue. Abolition of sumoylation of nucleoprotein significantly decreases homo-oligomerisation of the protein (Li et al, 2005)
(hasEvent)[Pathway:9694631] Maturation of nucleoprotein [Homo sapiens]
(precedingEvent)[Reaction:9694363] Dimerisation of nucleoprotein [Homo sapiens]
(replacementInstances)[_Deleted:9730598] Deletion of instance: 9694463
[Change default viewing format]
No pathways have been reviewed or authored by Nucleoprotein is SUMOylated (9729307)