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Details on Person Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3)

Class:Id	Reaction:9728723
_displayName	Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3)
_doRelease	TRUE
_timestamp	2021-08-08 13:13:23
authored	[InstanceEdit:9728724] May, Bruce, 2021-04-19
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9728717] May, Bruce, 2021-04-21
edited	[InstanceEdit:9728724] May, Bruce, 2021-04-19
input	[DefinedSet:444679] Sweet taste compounds [extracellular region] [Complex:9728735] TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:444632] Human receptors for sweet and umami taste [LiteratureReference:9728698] Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor [LiteratureReference:9728701] Modulation of sweet taste by umami compounds via sweet taste receptor subunit hT1R2 [LiteratureReference:9728703] The taste of D- and L-amino acids: In vitro binding assays with cloned human bitter (TAS2Rs) and sweet (TAS1R2/TAS1R3) receptors [LiteratureReference:9728726] Molecular mechanism of species-dependent sweet taste toward artificial sweeteners
modified	[InstanceEdit:9728759] May, Bruce, 2021-04-21 [InstanceEdit:9729188] May, Bruce, 2021-04-25 [InstanceEdit:9749950] May, Bruce, 2021-08-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3)
output	[Complex:9728706] TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] [Homo sapiens]
releaseDate	2021-09-15
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9728737] R-HSA-9728723.2
summation	[Summation:9729151] Sweet taste compounds (tastants) bind the sweet taste recept...
(hasEvent)	[Pathway:9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste [Homo sapiens]
(precedingEvent)	[Reaction:9728697] GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 [Homo sapiens]
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No pathways have been reviewed or authored by Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (9728723)