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Details on Person SLC5A2 binds gliflozins

Class:IdReaction:9728150
_displayNameSLC5A2 binds gliflozins
_doReleaseTRUE
_timestamp2022-05-10 17:57:29
authored[InstanceEdit:9728224] Jassal, Bijay, 2021-04-20
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9728224] Jassal, Bijay, 2021-04-20
definitionInhibition
edited[InstanceEdit:9728224] Jassal, Bijay, 2021-04-20
[InstanceEdit:9773839] Matthews, Lisa, 2022-05-10
input[EntityWithAccessionedSequence:429568] SLC5A2 [plasma membrane] [Homo sapiens]
[DefinedSet:9728134] gliflozins [extracellular region]
literatureReference[LiteratureReference:9728535] Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level
[LiteratureReference:9728553] Structural selectivity of human SGLT inhibitors
[LiteratureReference:9728561] Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters
modified[InstanceEdit:9728273] Jassal, Bijay, 2021-04-20
[InstanceEdit:9728508] Jassal, Bijay, 2021-04-21
[InstanceEdit:9728556] Jassal, Bijay, 2021-04-21
[InstanceEdit:9728560] Jassal, Bijay, 2021-04-21
[InstanceEdit:9773229] Matthews, Lisa, 2022-05-03
[InstanceEdit:9773839] Matthews, Lisa, 2022-05-10
[InstanceEdit:9773858] Matthews, Lisa, 2022-05-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC5A2 binds gliflozins
output[Complex:9728163] SLC5A2:gliflozins [plasma membrane] [Homo sapiens]
reactionType[DrugActionType:9725066] Inhibitor
releaseDate2022-06-09
reviewed[InstanceEdit:9767610] Huddart, Rachel, 2022-03-01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9728236] R-HSA-9728150.2
summation[Summation:9728530] The human gene SLC5A2 encodes sodium/glucose cotransporter 2...
(hasEvent)[Pathway:189200] Cellular hexose transport [Homo sapiens]
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No pathways have been reviewed or authored by SLC5A2 binds gliflozins (9728150)