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Details on Person keratinocyte of granulosum layer of epidermis

Class:Id	Cell:9727357
_displayName	keratinocyte of granulosum layer of epidermis
_timestamp	2023-07-07 14:47:04
cellType	[CellType:9725588] keratinocyte
created	[InstanceEdit:9727356] Orlic-Milacic, Marija, 2021-04-16
markerReference	[MarkerReference:9727997] Epidermal differentiation: the bare essentials [MarkerReference:9727996] Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis [MarkerReference:9727989] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin [MarkerReference:9727980] Expression of loricrin in skin disorders [MarkerReference:9728017] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin [MarkerReference:9728054] Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome [MarkerReference:9728025] KLK7 [cytosol] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum [MarkerReference:9728022] KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes [MarkerReference:9728013] HOPX [nucleoplasm] Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes [MarkerReference:9728035] PRSS3 [tertiary granule lumen] Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation [MarkerReference:9732200] FABP5 [cytosol] A histological and immunohistochemical study on chronic irritant contact dermatitis [MarkerReference:9824052] The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins [MarkerReference:9839497] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis [MarkerReference:9839511] Calmodulin-like skin protein: a new marker of keratinocyte differentiation [MarkerReference:9839567] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1 [MarkerReference:9839553] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1 [MarkerReference:9839578] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1 [MarkerReference:9839597] Multiple epidermal connexins are expressed in different keratinocyte subpopulations including connexin 31 [MarkerReference:9839626] Markers for Ca⁺⁺ -induced terminal differentiation of keratinocytes in vitro under defined conditions
modified	[InstanceEdit:9727427] Orlic-Milacic, Marija, 2021-04-16 [InstanceEdit:9728010] Orlic-Milacic, Marija, 2021-04-19 [InstanceEdit:9728067] Orlic-Milacic, Marija, 2021-04-20 [InstanceEdit:9732208] Orlic-Milacic, Marija, 2021-05-26 [InstanceEdit:9824068] Orlic-Milacic, Marija, 2023-01-14 [InstanceEdit:9839217] Orlic-Milacic, Marija, 2023-07-03 [InstanceEdit:9839502] Orlic-Milacic, Marija, 2023-07-06 [InstanceEdit:9839535] Orlic-Milacic, Marija, 2023-07-06 [InstanceEdit:9839548] Orlic-Milacic, Marija, 2023-07-06 [InstanceEdit:9839571] Orlic-Milacic, Marija, 2023-07-06 [InstanceEdit:9839587] Orlic-Milacic, Marija, 2023-07-07 [InstanceEdit:9839601] Orlic-Milacic, Marija, 2023-07-07 [InstanceEdit:9839636] Orlic-Milacic, Marija, 2023-07-07
name	keratinocyte of granulosum layer of epidermis keratinocyte of skin epidermis stratum granulosum
organ	[Anatomy:9725577] skin of body
proteinMarker	[EntityWithAccessionedSequence:6809649] KRT1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6809604] KRT10 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8849818] FLG(1-4061) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5216081] FABP5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6810848] LORICRIN [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6810837] IVL [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9727987] SPINK5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9727975] KLK7 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8934778] KLK5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9728002] HOPX [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6800432] PRSS3 [tertiary granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:8934850] SPRR2A [cornified envelope] [Homo sapiens] [EntityWithAccessionedSequence:431723] AQP3 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9839523] CALML5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9839542] DMKN [secretory granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:9839543] KRTDAP [secretory granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:9839544] SBSN [secretory granule lumen] [Homo sapiens] [EntityWithAccessionedSequence:9839595] GJB3 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9839614] KPRP [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9727366] R-HSA-9727357.1
tissue	[Anatomy:9725551] skin epidermis
tissueLayer	[Anatomy:9727362] stratum granulosum of epidermis
(cell)	[MarkerReference:9727980] Expression of loricrin in skin disorders [MarkerReference:9727989] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin [MarkerReference:9727996] Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis [MarkerReference:9727997] Epidermal differentiation: the bare essentials [MarkerReference:9728013] HOPX [nucleoplasm] Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes [MarkerReference:9728017] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin [MarkerReference:9728022] KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes [MarkerReference:9728025] KLK7 [cytosol] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum [MarkerReference:9728035] PRSS3 [tertiary granule lumen] Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation [MarkerReference:9728054] Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome List all 19 refering instances
(input)	[CellDevelopmentStep:9727355] Keratinocyte of granulosum layer differentiates into corneocyte of corneum layer in interfollicular epidermis [Homo sapiens]
(output)	[CellDevelopmentStep:9727359] Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis [Homo sapiens]
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No pathways have been reviewed or authored by keratinocyte of granulosum layer of epidermis (9727357)