Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person SCN2A in combination with a regulatory beta subunit responds...
| Class:Id | Summation:9725726 |
|---|---|
| _displayName | SCN2A in combination with a regulatory beta subunit responds... |
| _timestamp | 2021-03-31 14:24:14 |
| created | [InstanceEdit:9725724] May, Bruce, 2021-03-31 |
| literatureReference | [LiteratureReference:9724821] Voltage-gated sodium channels in taste bud cells |
| text | SCN2A in combination with a regulatory beta subunit responds to depolarization by opening and passively transporting sodium ions according to the concentration gradient from the extracellular region to the cytosol (Ahmed et al. 1992, Ben-Shalom et al. 2017). In mouse type II taste cells, initial depolarization at the apex of the cell is believed to cause an activation potential via Scn2a, Scn3a, and Scn9a located at the basolateral membrane (Gao et al. 2009). Differences in SCN2A alleles appear to be related to autism spectrum disorder (Ben-Shalom et al. 2017). |
| (summation) | [Reaction:9717396] SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by SCN2A in combination with a regulatory beta subunit responds... (9725726)
