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Details on Person The Calhm1 channel transports ATP across the plasma membrane...
| Class:Id | Summation:9725723 |
|---|---|
| _displayName | The Calhm1 channel transports ATP across the plasma membrane... |
| _timestamp | 2021-03-31 14:24:13 |
| created | [InstanceEdit:9725724] May, Bruce, 2021-03-31 |
| text | The Calhm1 channel transports ATP across the plasma membrane in response to depolarization of the membrane (Taruno et al. 2013). Heteromeric complexes containing both Calhm1 and Calhm3 have voltage-gating that is faster than homomeric Calhm1 complexes and resembles the voltage gating observed in vivo (Ma et al. 2018). In mice, knockout of Calhm1 strongly affected voltage-gated currents associated with ATP release (Ma et al. 2017) and Calhm1 and Calhm3 are sorted to the basolateral membrane of taste cells (Kashio et al. 2019). |
| (summation) | [Reaction:9717434] Calhm1:Calhm3 transports ATP from the cytosol to the extracellular region [Mus musculus] |
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