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Details on Person transit-amplifying cell of epidermis basal layer

Class:Id	Cell:9725625
_displayName	transit-amplifying cell of epidermis basal layer
_timestamp	2023-07-06 11:58:55
cellType	[CellType:9725588] keratinocyte
created	[InstanceEdit:9725578] Orlic-Milacic, Marija, 2021-03-29
literatureReference	[LiteratureReference:9725617] Delayed onset of epidermal differentiation in psoriasis [LiteratureReference:9725598] Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study [LiteratureReference:9725607] K15 expression implies lateral differentiation within stratified epithelial basal cells [LiteratureReference:9725585] Keratinocyte Differentiation by Flow Cytometry [LiteratureReference:9725620] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression
markerReference	[MarkerReference:9725601] Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin-filament network involving keratins K5 and K14 [MarkerReference:9725550] K15 expression implies lateral differentiation within stratified epithelial basal cells [MarkerReference:9725597] KRT78 [cytosol] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression [MarkerReference:9725579] Delayed onset of epidermal differentiation in psoriasis [MarkerReference:9839321] Location and phenotype of human adult keratinocyte stem cells of the skin [MarkerReference:9839322] Enrichment for murine keratinocyte stem cells based on cell surface phenotype [MarkerReference:9839486] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis
modified	[InstanceEdit:9727353] Orlic-Milacic, Marija, 2021-04-16 [InstanceEdit:9727370] Orlic-Milacic, Marija, 2021-04-16 [InstanceEdit:9731154] Orlic-Milacic, Marija, 2021-05-13 [InstanceEdit:9839328] Orlic-Milacic, Marija, 2023-07-05 [InstanceEdit:9839502] Orlic-Milacic, Marija, 2023-07-06
name	transit-amplifying cell of epidermis basal layer keratinocyte of basal layer of epidermis keratinocyte of skin epidermis stratum basale
organ	[Anatomy:9725577] skin of body
proteinMarker	[EntityWithAccessionedSequence:446074] KRT5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:446091] KRT14 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6809589] KRT15 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6809631] KRT78 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:204439] ITGA6(24-1130) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:917983] TFRC(1-760) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:431723] AQP3 [plasma membrane] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9725631] R-HSA-9725625.1
tissue	[Anatomy:9725551] skin epidermis
tissueLayer	[Anatomy:9725619] stratum basale of epidermis
(cell)	[MarkerReference:9725550] K15 expression implies lateral differentiation within stratified epithelial basal cells [MarkerReference:9725579] Delayed onset of epidermal differentiation in psoriasis [MarkerReference:9725597] KRT78 [cytosol] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression [MarkerReference:9725601] Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin-filament network involving keratins K5 and K14 [MarkerReference:9839321] Location and phenotype of human adult keratinocyte stem cells of the skin [MarkerReference:9839322] Enrichment for murine keratinocyte stem cells based on cell surface phenotype [MarkerReference:9839486] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis
(input)	[CellDevelopmentStep:9727354] Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis [Homo sapiens]
(output)	[CellDevelopmentStep:9725621] Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis [Homo sapiens]
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No pathways have been reviewed or authored by transit-amplifying cell of epidermis basal layer (9725625)