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Details on Person NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [nucleoplasm]

Class:Id	Complex:9725012
_displayName	NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [nucleoplasm]
_timestamp	2021-03-26 16:38:50
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9725011] Rothfels, Karen, 2021-03-26
disease	[Disease:1500689] cancer
hasComponent	[EntityWithAccessionedSequence:9725010] NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9725010] NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] [Homo sapiens]
name	NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9725016] R-HSA-9725012.1
(hasComponent)	[Complex:9725021] NPM1-p-7Y ALK fusion dimer:CUL1:RBX1:SKP1:ZC3HC1 [nucleoplasm] [Homo sapiens] [Complex:9725027] NPM1p-7Y ALK fusion dimer:CUL1:RBX1:SKP1:p-S354 ZC3HC1 [nucleoplasm] [Homo sapiens] [Complex:9850901] NPM1-ALK;NPM1:FOXM1 [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9725023] NPM1-ALK fusion dimer binds SKP1:CUL1:RBX1:ZC3HC1 [Homo sapiens] [Reaction:9851090] NPM1-ALK binds NPM1 and FOXM1 [Homo sapiens]
(output)	[BlackBoxEvent:9725009] NPM1-ALK translocates to the nucleus [Homo sapiens]
(regulator)	[PositiveGeneExpressionRegulation:9725337] Positive gene expression regulation by 'NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [nucleoplasm]' [NegativeRegulation:9850973] Negative regulation by 'NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [nucleoplasm]'
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No pathways have been reviewed or authored by NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [nucleoplasm] (9725012)