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Details on Person Rothfels, Karen, 2021-03-22

Class:Id	InstanceEdit:9724184
_displayName	Rothfels, Karen, 2021-03-22
_timestamp	2021-03-22 21:37:54
author	[Person:1226097] Rothfels, Karen
dateTime	2021-03-22 21:37:49
(modified)	[Reaction:9700190] ALK mutants bind SHC [Homo sapiens] [PathwayDiagram:9700218] Diagram of Signaling by ALK, Signaling by ALK fusions and activated point mutants, ALK mutants bind TKIs, ASP-3026- resistant ALK mutants, NVP-TAE684-resistant ALK mutants, alectinib resistant ALK mutants, brigatinib-resistant ALK mutants, ceritinib-resistant ALK mutants, crizotinib-resistant ALK mutants, and lorlatinib-resistant ALK mutants [CandidateSet:9710874] GRB2- and PLC gamma-binding ALK fusion protein dimers [cytosol] [Homo sapiens] [CandidateSet:9711929] PI3K-binding ALK mutants [cytosol] [Homo sapiens] [CandidateSet:9711944] STAT3-activating ALK mutants [cytosol] [Homo sapiens] [Reaction:9712079] ALK mutants bind STAT3 [Homo sapiens] [CandidateSet:9713538] SHC-binding ALK mutant dimers [cytosol] [Homo sapiens] [Summation:9724095] The STAT3 signaling pathway is a major downstream target of ... [Summation:9724106] Early studies with the NPM-ALK fusion identified two putativ... [Summation:9724127] Various ALK fusions and point mutants have been shown to for...
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No pathways have been reviewed or authored by Rothfels, Karen, 2021-03-22 (9724184)