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Details on Person ALK T1087I [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9723874
_displayName	ALK T1087I [plasma membrane]
_timestamp	2021-03-18 18:20:01
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9723871] Rothfels, Karen, 2021-03-18
disease	[Disease:9671652] neuroblastoma
endCoordinate	1620
hasModifiedResidue	[ReplacedResidue:9723863] L-threonine 1087 replaced with L-isoleucine
literatureReference	[LiteratureReference:9723288] Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma [LiteratureReference:9700372] Oncogenic mutations of ALK kinase in neuroblastoma
name	ALK T1087I ALK tyrosine kinase receptor ALK_HUMAN
referenceEntity	[ReferenceGeneProduct:49894] UniProt:Q9UM73 ALK [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9723879] R-HSA-9723874.1
startCoordinate	19
(hasComponent)	[Complex:9723875] ALK T1087I dimer [plasma membrane] [Homo sapiens]
(hasMember)	[CandidateSet:9700559] juxtamembrane domain ALK mutants [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by ALK T1087I [plasma membrane] (9723874)