Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GGPS1 hexamer transfers IPPP to GPP

Class:Id	Reaction:9717830
_displayName	GGPS1 hexamer transfers IPPP to GPP
_doRelease	TRUE
_timestamp	2025-06-06 20:51:48
authored	[InstanceEdit:191754] Jassal, B, 2007-01-24 15:15:12
catalystActivity	[CatalystActivity:9717839] (2E,6E)-farnesyl diphosphate synthase activity of holo-GGPS1 hexamer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9717837] Jassal, Bijay, 2021-03-15
crossReference	[DatabaseIdentifier:9945085] RHEA:19362
edited	[InstanceEdit:191754] Jassal, B, 2007-01-24 15:15:12
input	[SimpleEntity:191409] GPP [cytosol] [SimpleEntity:191362] IPPP [cytosol]
literatureReference	[LiteratureReference:191398] Human geranylgeranyl diphosphate synthase. cDNA cloning and expression. [LiteratureReference:191275] Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression [LiteratureReference:981558] The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs
modified	[InstanceEdit:9730937] Jassal, Bijay, 2021-05-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9945102] D'Eustachio, Peter, 2025-04-10 [InstanceEdit:9954123] D'Eustachio, Peter, 2025-06-06
name	GGPS1 hexamer transfers IPPP to GPP isopentenyl diphosphate + (2E)-geranyl diphosphate => (2E,6E)-farnesyl diphosphate + diphosphate Another isopentenyl pyrophosphate is added to geranyl pyrophosphate
output	[SimpleEntity:191385] FAPP [cytosol] [SimpleEntity:111294] PPi [cytosol]
precedingEvent	[Reaction:9717834] GGPS1 hexamer transfers IPPP to DMAPP [Homo sapiens] [Reaction:191382] Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate [Homo sapiens] [Reaction:191414] MVD decarboxylates MVA5PP to IPPP [Homo sapiens] [Reaction:191322] FDPS dimer transfers IPPP to DMAPP [Homo sapiens] [Reaction:191382] Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate [Homo sapiens] [Reaction:191414] MVD decarboxylates MVA5PP to IPPP [Homo sapiens] [Reaction:191414] MVD decarboxylates MVA5PP to IPPP [Homo sapiens] [Reaction:191422] Mevalonate-5-phosphate is further phosphorylated [Homo sapiens]
releaseDate	2007-02-20
reviewed	[InstanceEdit:191591] D'Eustachio, P, 2007-01-22 01:32:07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9717848] R-HSA-9717830.4
summation	[Summation:191267] Further condensation of an isopentenyl pyrophosphate (IPPP) ...
(hasEvent)	[Pathway:9969896] Lanosterol biosynthesis [Homo sapiens]
(precedingEvent)	[Reaction:191405] Two FAPP molecules dimerize to form presqualene diphosphate [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9971931] Update Tracker - [Reaction:9717830] GGPS1 hexamer transfers IPPP to GPP - v95:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by GGPS1 hexamer transfers IPPP to GPP (9717830)