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Details on Person Dephosphorylation of DDX58

Class:IdReaction:9717588
_displayNameDephosphorylation of DDX58
_timestamp2021-03-13 04:11:28
catalystActivity[CatalystActivity:9717597] protein serine/threonine phosphatase activity of PPP1CA, PPP1CC [cytosol]
catalystActivityReference[CatalystActivityReference:9717608] protein serine phosphatase activity of PPP1CA, PPP1CC [cytosol] Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling
compartment[Compartment:70101] cytosol
created[InstanceEdit:9717591] Shamovsky, Veronica, 2021-03-13
input[SimpleEntity:29356] H2O [cytosol]
[EntityWithAccessionedSequence:9717586] p-S8,T170-DDX58 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9717589] Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling
nameDephosphorylation of DDX58
output[SimpleEntity:113550] Pi [nucleoplasm]
[EntityWithAccessionedSequence:168917] DDX58 [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9717635] R-HSA-9717588.1
summation[Summation:9717594] Antiviral innate immune response receptor RIG-I (RIG-1, DDX5...
(hasEvent)[Pathway:9717624] Regulators of DDX58/IFIH1 signaling [Homo sapiens]
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