Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG

Class:Id	Reaction:9717576
_displayName	Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG
_doRelease	TRUE
_timestamp	2021-08-08 13:07:17
authored	[InstanceEdit:9717459] May, Bruce, 2021-03-10
catalystActivity	[CatalystActivity:9717571] phosphatidylinositol-4,5-bisphosphate phospholipase C activity of Gnb1:GNG2:PLCB2:Ca2+ [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9717561] May, Bruce, 2021-03-12
edited	[InstanceEdit:9717459] May, Bruce, 2021-03-10
input	[SimpleEntity:29356] H2O [cytosol] [SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
isChimeric	TRUE
literatureReference	[LiteratureReference:398047] Regulatory interactions between the amino terminus of G-protein betagamma subunits and the catalytic domain of phospholipase Cbeta2 [LiteratureReference:9717198] Characterization of a phospholipase C beta 2-binding site near the amino-terminal coiled-coil of G protein beta gamma subunits [LiteratureReference:9717195] Identification of a structural element in phospholipase C beta2 that interacts with G protein betagamma subunits [LiteratureReference:9717181] Phospholipase C beta2 association with phospholipid interfaces assessed by fluorescence resonance energy transfer. G protein betagamma subunit-mediated translocation is not required for enzyme activation [LiteratureReference:9717190] Role of the gamma subunit prenyl moiety in G protein beta gamma complex interaction with phospholipase Cbeta
modified	[InstanceEdit:9725196] May, Bruce, 2021-03-29 [InstanceEdit:9749950] May, Bruce, 2021-08-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG
output	[SimpleEntity:114519] DAG [plasma membrane] [SimpleEntity:114520] I(1,4,5)P3 [cytosol]
releaseDate	2021-09-15
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48898] Bos taurus [Species:48887] Homo sapiens [Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:9717583] R-NUL-9717576.2
summation	[Summation:9725120] The binding of the gustducin beta-gamma complex (Gnb1,3:GNG1...
(inferredFrom)	[Reaction:9717205] GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG (9717576)