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Details on Person TKI sensitivity patterns of novel kinase-domain mutations suggest therapeutic opportunities for patients with resistant ALK+ tumors

Class:Id	LiteratureReference:9717267
_displayName	TKI sensitivity patterns of novel kinase-domain mutations suggest therapeutic opportunities for patients with resistant ALK+ tumors
_timestamp	2021-03-08 22:33:19
author	[Person:9717249] Amin, Amit Dipak [Person:9717253] Li, Lingxiao [Person:9717251] Rajan, Soumya S [Person:9717257] Gokhale, Vijay [Person:9717256] Groysman, Matthew J [Person:9717263] Pongtornpipat, Praechompoo [Person:9717260] Tapia, Edgar O [Person:9717261] Wang, Mengdie [Person:9717255] Schatz, Jonathan H
created	[InstanceEdit:9717266] Rothfels, Karen, 2021-03-08
journal	Oncotarget
pages	23715-29
pubMedIdentifier	27009859
title	TKI sensitivity patterns of novel kinase-domain mutations suggest therapeutic opportunities for patients with resistant ALK+ tumors
volume	7
year	2016
(literatureReference)	[FailedReaction:9700646] ASP-3026- resistant ALK mutants don't bind ASP-3026 [Homo sapiens] [FailedReaction:9700658] ceritinib-resistant ALK mutants don't bind ceritinib [Homo sapiens] [FailedReaction:9715356] brigatinib-resistant ALK mutants don't bind brigatinib [Homo sapiens] [Pathway:9717264] ASP-3026-resistant ALK mutants [Homo sapiens] [DefinedSet:9700553] ceritinib-resistant ALK mutants [plasma membrane] [Homo sapiens] [DefinedSet:9700568] NVP-TAE684-resistant ALK mutants [plasma membrane] [Homo sapiens] [DefinedSet:9717270] ASP3026-resistant ALK mutants [plasma membrane] [Homo sapiens]
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