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Details on Person I(1,4,5)P3 binds ITPR3 tetramer

Class:Id	Reaction:9717214
_displayName	I(1,4,5)P3 binds ITPR3 tetramer
_doRelease	TRUE
_timestamp	2021-08-08 13:07:33
authored	[InstanceEdit:9717176] May, Bruce, 2021-03-05
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9717219] May, Bruce, 2021-03-08
edited	[InstanceEdit:9717176] May, Bruce, 2021-03-05
input	[Complex:112292] IP3-gated Ca-channel type 3 [endoplasmic reticulum membrane] [Homo sapiens] [SimpleEntity:114520] I(1,4,5)P3 [cytosol] [SimpleEntity:114520] I(1,4,5)P3 [cytosol] [SimpleEntity:114520] I(1,4,5)P3 [cytosol] [SimpleEntity:114520] I(1,4,5)P3 [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9717567] Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium [LiteratureReference:9717557] Structural basis for the regulation of inositol trisphosphate receptors by Ca²⁺ and IP₃ [LiteratureReference:9717578] Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptors
modified	[InstanceEdit:9717584] May, Bruce, 2021-03-12 [InstanceEdit:9725649] May, Bruce, 2021-03-29 [InstanceEdit:9749950] May, Bruce, 2021-08-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	I(1,4,5)P3 binds ITPR3 tetramer
output	[Complex:112291] IP3-gated Ca-channel type 3 (open) [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:9717205] GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG [Homo sapiens] [Reaction:9717193] GNB1,3:GNG13 binds PLCB2:Ca2+ [Homo sapiens]
releaseDate	2021-09-15
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9717239] R-HSA-9717214.2
summation	[Summation:9725648] One molecule of inositol 1,4,5-trisphosphate (I(1,4,5)P3) bi...
(hasEvent)	[Pathway:9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste [Homo sapiens]
(precedingEvent)	[Reaction:9717215] ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol [Homo sapiens]
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No pathways have been reviewed or authored by I(1,4,5)P3 binds ITPR3 tetramer (9717214)