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Details on Person Abatacept binds to CD86

Class:Id	Reaction:9716516
_displayName	Abatacept binds to CD86
_doRelease	FALSE
_timestamp	2021-02-22 15:37:10
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9716514] Stephan, Ralf, 2021-02-22
input	[ProteinDrug:9716501] abatacept [extracellular region] [EntityWithAccessionedSequence:179784] CD86 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9716521] CTLA-4 is a second receptor for the B cell activation antigen B7 [LiteratureReference:9716511] Update on the use of abatacept for the treatment of rheumatoid arthritis [LiteratureReference:9716515] Abatacept: a novel treatment for moderate-to-severe rheumatoid arthritis [LiteratureReference:9716502] Long-term safety of subcutaneous abatacept in rheumatoid arthritis: integrated analysis of clinical trial data representing more than four years of treatment
name	Abatacept binds to CD86 Abatacept binds to B7-2
output	[Complex:9716520] abatacept:CD86 [extracellular region] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9716528] R-HSA-9716516.1
summation	[Summation:9716498] Abatacept (CTLA-4-Ig) binds to both CD80 dimer (B7-1 dimer) ...
(hasEvent)	[Pathway:389356] Co-stimulation by CD28 [Homo sapiens]
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No pathways have been reviewed or authored by Abatacept binds to CD86 (9716516)