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Details on Person Dimethyl fumarate modifies Cys191 in GSDMD

Class:IdReaction:9716258
_displayNameDimethyl fumarate modifies Cys191 in GSDMD
_doReleaseTRUE
_timestamp2022-06-10 19:52:56
authored[InstanceEdit:9706708] Shamovsky, Veronica, 2020-11-09
compartment[Compartment:70101] cytosol
created[InstanceEdit:9716268] Shamovsky, Veronica, 2021-02-19
edited[InstanceEdit:9715950] Shorser, Solomon, 2021-02-17
input[EntityWithAccessionedSequence:6801577] GSDMD [cytosol] [Homo sapiens]
[CandidateSet:9716226] fumarate analogs [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9716211] Succination inactivates gasdermin D and blocks pyroptosis
modified[InstanceEdit:9716570] Shamovsky, Veronica, 2021-02-22
[InstanceEdit:9716796] Shamovsky, Veronica, 2021-02-25
[InstanceEdit:9728823] Shamovsky, Veronica, 2021-04-22
[InstanceEdit:9793347] Shamovsky, Veronica, 2022-06-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDimethyl fumarate modifies Cys191 in GSDMD
output[EntityWithAccessionedSequence:9716198] S-(2-succinyl)-C191-GSDMD [cytosol] [Homo sapiens]
releaseDate2021-03-23
reviewed[InstanceEdit:9715448] Kanneganti, Thirumala-Devi, 2021-02-17
[InstanceEdit:9728818] Shao, Feng, 2021-04-22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9716270] R-HSA-9716258.4
summation[Summation:9716221] During inflammation, the inflammatory caspase‑1 (CASP1) can ...
(hasEvent)[Pathway:5620971] Pyroptosis [Homo sapiens]
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