Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q9JJG7-2 Caln1

Class:IdReferenceIsoform:9715487
_chainChangeLogchain:1-261 for 9715487 added on Wed February 17 2021
_displayNameUniProt:Q9JJG7-2 Caln1
_timestamp2023-11-03 18:22:06
chainchain:1-261
checksumD38AE0DFBBAE38D9
commentFUNCTION Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.SUBUNIT Interacts with PI4KB. This binding competes with FREQ/NCS1 binding in a calcium-dependent manner.SUBCELLULAR LOCATION Brain-specific. High expression in the cerebellum, hippocampus, and cortex.DEVELOPMENTAL STAGE Shows little prenatal expression, with highest expression at postnatal day 21.DOMAIN The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.SEQUENCE CAUTION Truncated N-terminus.
created[InstanceEdit:9715482] Weiser, JD
descriptionrecommendedName: Calcium-binding protein 8 shortName: CaBP8 alternativeName: Calneuron I alternativeName: Calneuron-1
geneNameCaln1
Cabp8
MNCb-0849
identifierQ9JJG7
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
Calcium
Cell membrane
Cytoplasm
Golgi apparatus
Membrane
Metal-binding
Reference proteome
Repeat
Transmembrane
Transmembrane helix
modified[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameCaln1
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierCABP8_MOUSE
F8WHE1
sequenceLength261
species[Species:48892] Mus musculus
variantIdentifierQ9JJG7-2
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No pathways have been reviewed or authored by UniProt:Q9JJG7-2 Caln1 (9715487)