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Details on Person Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib
| Class:Id | LiteratureReference:9715259 |
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| _displayName | Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib |
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| _timestamp | 2021-02-17 00:33:26 |
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| author | [Person:6806119] Katayama, Ryohei
[Person:9700335] Friboulet, Luc
[Person:9715245] Koike, Sumie
[Person:9700347] Lockerman, Elizabeth L
[Person:9700379] Khan, Tahsin M
[Person:9700406] Gainor, Justin F
[Person:5250764] Iafrate, A John
[Person:9699708] Takeuchi, Kengo
[Person:9715250] Taiji, Makoto
[Person:9715241] Okuno, Yasushi
[Person:9700375] Fujita, Naoya
[Person:9029753] Engelman, Jeffrey A
[Person:9700355] Shaw, Alice T |
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| created | [InstanceEdit:9715244] Rothfels, Karen, 2021-02-17 |
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| journal | Clin Cancer Res |
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| pages | 5686-96 |
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| pubMedIdentifier | 25228534 |
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| title | Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib |
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| volume | 20 |
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| year | 2014 |
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| (literatureReference) | [Reaction:9700131] ALK mutants bind type I TKIs [Homo sapiens]
[FailedReaction:9700646] ASP-3026- resistant ALK mutants don't bind ASP-3026 [Homo sapiens]
[FailedReaction:9700656] alectinib resistant ALK mutants don't bind alectinib [Homo sapiens]
[FailedReaction:9715356] brigatinib-resistant ALK mutants don't bind brigatinib [Homo sapiens]
[Pathway:9717264] ASP-3026-resistant ALK mutants [Homo sapiens]
[DefinedSet:9700552] brigatinib-sensitive ALK mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9700560] alectinib resistant ALK mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9714046] brigatinib-resistant ALK mutants [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9715261] ALK V1180L [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9715289] p-7Y ALK V1180L [plasma membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib (9715259)
