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Details on Person Ano1 dimer binds Ca2+

Class:IdReaction:9714790
_displayNameAno1 dimer binds Ca2+
_doReleaseTRUE
_timestamp2021-08-02 08:33:27
authored[InstanceEdit:9714718] May, Bruce, 2021-02-13
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9714800] May, Bruce, 2021-02-14
edited[InstanceEdit:9714718] May, Bruce, 2021-02-13
input[Complex:9714819] Ano1 dimer [plasma membrane] [Mus musculus]
[SimpleEntity:74016] Ca2+ [cytosol]
[SimpleEntity:74016] Ca2+ [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9714812] EF-hand like Region in the N-terminus of Anoctamin 1 Modulates Channel Activity by Ca2+ and Voltage
[LiteratureReference:9714795] Cryo-EM structures of the TMEM16A calcium-activated chloride channel
[LiteratureReference:9714808] Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
[LiteratureReference:9714820] Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
modified[InstanceEdit:9714834] May, Bruce, 2021-02-15
[InstanceEdit:9749377] May, Bruce, 2021-08-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAno1 dimer binds Ca2+
output[Complex:9714822] Ano1 dimer:Ca2+ [plasma membrane] [Mus musculus]
releaseDate2021-09-15
reviewed[InstanceEdit:9749366] Raimondi, Francesco, 2021-08-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9714827] R-MMU-9714790.2
summation[Summation:9714831] Each monomer of the Ano1 dimer (Tmem16a dimer) can bind up t...
(inferredFrom)[Reaction:9712195] ANO2 dimer binds Ca2+ [Homo sapiens]
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