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Details on Person Secondary mutations at I1171 in the ALK gene confer resistance to both Crizotinib and Alectinib

Class:IdLiteratureReference:9713997
_displayNameSecondary mutations at I1171 in the ALK gene confer resistance to both Crizotinib and Alectinib
_timestamp2021-02-02 01:31:50
author[Person:9713995] Toyokawa, Gouji
[Person:9714000] Hirai, Fumihiko
[Person:9713991] Inamasu, Eiko
[Person:9713994] Yoshida, Tsukihisa
[Person:9713998] Nosaki, Kaname
[Person:9713993] Takenaka, Tomoyoshi
[Person:9713992] Yamaguchi, Masafumi
[Person:9713996] Seto, Takashi
[Person:9713989] Takenoyama, Mitsuhiro
[Person:9713999] Ichinose, Yukito
created[InstanceEdit:9713990] Rothfels, Karen, 2021-02-02
journalJ Thorac Oncol
pagese86-7
pubMedIdentifier25393798
titleSecondary mutations at I1171 in the ALK gene confer resistance to both Crizotinib and Alectinib
volume9
year2014
(literatureReference)[DefinedSet:9700564] crizotinib resistant ALK mutants [plasma membrane] [Homo sapiens]
[FailedReaction:9700656] alectinib resistant ALK mutants don't bind alectinib [Homo sapiens]
[FailedReaction:9715357] crizotinib-resistant ALK mutants don't bind crizotinib [Homo sapiens]
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No pathways have been reviewed or authored by Secondary mutations at I1171 in the ALK gene confer resistance to both Crizotinib and Alectinib (9713997)