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Details on Person cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol

Class:Id	Reaction:9713672
_displayName	cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol
_doRelease	TRUE
_timestamp	2021-08-18 13:17:10
authored	[InstanceEdit:9713590] May, Bruce, 2021-01-26
catalystActivity	[CatalystActivity:9713741] monoatomic cation channel activity of cAMP:Olfactory CNG channel [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9713669] May, Bruce, 2021-01-31
edited	[InstanceEdit:9713590] May, Bruce, 2021-01-26
input	[SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:9713677] Olfactory marker protein captures cAMP produced via Gαs-protein-coupled receptor activation [LiteratureReference:9713738] Olfactory marker protein modulates the cAMP kinetics of the odour-induced response in cilia of mouse olfactory receptor neurons [LiteratureReference:9713700] Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping
modified	[InstanceEdit:9714718] May, Bruce, 2021-02-13 [InstanceEdit:9749377] May, Bruce, 2021-08-02 [InstanceEdit:9751116] May, Bruce, 2021-08-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol
output	[SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:74016] Ca2+ [cytosol]
releaseDate	2021-09-15
reviewed	[InstanceEdit:9749366] Raimondi, Francesco, 2021-08-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9713760] R-MMU-9713672.2
summation	[Summation:9714708] The olfactory cyclic nucleotide-gated channel (CNG channel) ...
(inferredFrom)	[Reaction:9712190] cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol [Homo sapiens]
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