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Details on Person IRS- and FRS-binding ALK fusion proteins [cytosol]

Class:Id	CandidateSet:9713536
_displayName	IRS- and FRS-binding ALK fusion proteins [cytosol]
_timestamp	2021-08-19 00:11:54
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9713535] Rothfels, Karen, 2021-01-26
disease	[Disease:1500689] cancer
hasCandidate	[Complex:9730706] NPM1(1-117)-p-7Y ALK(1068-1620) fusion dimer [cytosol] [Homo sapiens]
hasMember	[Complex:9699991] NPM1(1-117)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:9699737] Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway [LiteratureReference:9730688] Molecular detection of the (2;5) translocation of non-Hodgkin's lymphoma by reverse transcriptase-polymerase chain reaction
modified	[InstanceEdit:9730713] Rothfels, Karen, 2021-05-10 [InstanceEdit:9751186] Rothfels, Karen, 2021-08-19
name	IRS- and FRS-binding ALK fusion proteins
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9713537] R-HSA-9713536.2
(hasComponent)	[Complex:9711938] ALK fusions:FRS [cytosol] [Homo sapiens] [Complex:9711940] IRS:ALK fusion proteins [cytosol] [Homo sapiens] [Complex:9712069] ALK fusions:p-6Y FRS [cytosol] [Homo sapiens] [Complex:9712076] p-Y IRS1:ALK fusion proteins [cytosol] [Homo sapiens]
(input)	[Reaction:9712081] ALK fusions bind FRS [Homo sapiens] [Reaction:9712088] ALK fusion proteins bind IRS [Homo sapiens]
(replacementInstances)	[_Deleted:9751189] Deletion of instance: 9713533
(updatedInstance)	[_UpdateTracker:9902668] Update Tracker - [CandidateSet:9713536] IRS- and FRS-binding ALK fusion proteins [cytosol] - v78:[modifyName]
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No pathways have been reviewed or authored by IRS- and FRS-binding ALK fusion proteins [cytosol] (9713536)