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Details on Person ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region

Class:Id	Reaction:9712204
_displayName	ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region
_doRelease	TRUE
_timestamp	2021-08-02 08:32:40
authored	[InstanceEdit:9712175] May, Bruce, 2021-01-16
catalystActivity	[CatalystActivity:9712196] chloride channel activity of ANO2:Ca2+ [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9712180] May, Bruce, 2021-01-16
edited	[InstanceEdit:9712175] May, Bruce, 2021-01-16
inferredFrom	[Reaction:9714186] Ano2 dimer:Ca2+ translocates Cl- from the cytosol to the extracellular region [Mus musculus]
input	[SimpleEntity:352022] Cl- [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9714811] TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals
modified	[InstanceEdit:9714220] May, Bruce, 2021-02-06 [InstanceEdit:9714828] May, Bruce, 2021-02-14 [InstanceEdit:9714834] May, Bruce, 2021-02-15 [InstanceEdit:9749377] May, Bruce, 2021-08-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region
output	[SimpleEntity:188972] Cl- [extracellular region]
precedingEvent	[Reaction:9712195] ANO2 dimer binds Ca2+ [Homo sapiens] [Reaction:9712190] cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol [Homo sapiens]
releaseDate	2021-09-15
reviewed	[InstanceEdit:9749366] Raimondi, Francesco, 2021-08-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9712221] R-HSA-9712204.2
summation	[Summation:9714830] Each monomer of the ANO2 dimer contains a pore that transloc...
(hasEvent)	[Pathway:381753] Olfactory Signaling Pathway [Homo sapiens]
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No pathways have been reviewed or authored by ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region (9712204)